Isa Berger was born in 1988 in Orșova. She graduated from the "Nikolaus Lenau" High School in Timișoara and has a Bachelor's degree in International Relations and European Studies at the Faculty of Philosophy, Political Science and Communication Sciences in Timișoara. She then studied acting in German, specialising in Performing Arts - Acting in German at the Faculty of Music and Theatre of the West University of Timisoara. She has been a member of the TGST ensemble since 2013.

More recently, she has appeared and continues to appear in productions such as The Snow Queen by Yevgeny Schwarz as the young Gerda, Leonce and Lena by Georg Büchner as Princess Lena of the kingdom of Pipi, The Jungle Book after Rudyard Kipling as Raschka the she-wolf, A Midsummer Night's Dream after William Shakespeare as Moth, The Dragon by Yevgeny Schwarz as Elsa, The Theatre by Pascal Rambert as Ina, Nadirs by Herta Müller as the Storyteller.

She has worked with directors such as Alexander Hausvater, István K. Szabó, Laszlo Bocśardi, Yuri Kordonsky, Silviu Purcărete, Peter Kerek, Cristian Ban, Lászlo Béréș, Răzvan Mazilu, Niky Wolcz, Kristóf Szabó, Volker Schmidt, Pascal Rambert.

She has achieved outstanding merits in theatre pedagogy, especially in the coordination of the activities of the theatre troupes of the "Nikolaus Lenau" High School and the International German-speaking School and Youth Theatre Festival.

In 2016, she received the "Stefan Jäger" Award for special achievements at the German State Theatre Timisoara and the German Youth Theatre. In 2017 she was awarded the "Pro Cultura Timisiensis" prize for special achievements in the cultural field.

She participated in various acting workshops led by Simon Schlingplässer, Radu Alexandru Nica, Alexander Hausvater, Ida Jarcsek-Gaza, Miklós Bács, Andrea Gavriliu or Ștefan Lupu. Isa Berger also cooperated with the Mihai Eminescu National Theatre of Timişoara and the Merlin Children's and Youth Theatre of Timişoara, as well as with the "I. D. Sîrbu" Dramatic Theater from Petroșani. Furthermore, she appeared in feature and short films.